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	<title>PBDE Archives - One Earth - One Ocean e. V.</title>
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	<title>PBDE Archives - One Earth - One Ocean e. V.</title>
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		<title>The influence of microplastics and halogenated contaminants in feed on toxicokinetics and gene expression in European seabass (Dicentrarchus labrax)</title>
		<link>https://oneearth-oneocean.com/international-marine-litter-database/2021/the-influence-of-microplastics-and-halogenated-contaminants-in-feed-on-toxicokinetics-and-gene-expression-in-european-seabass-dicentrarchus-labrax/</link>
		
		<dc:creator><![CDATA[Birgit Westermayr]]></dc:creator>
		<pubDate>Fri, 27 Aug 2021 10:06:45 +0000</pubDate>
				<category><![CDATA[INTERNATIONAL MARINE LITTER DATABASE]]></category>
		<category><![CDATA[elimination]]></category>
		<category><![CDATA[gene expression]]></category>
		<category><![CDATA[microplastics]]></category>
		<category><![CDATA[PBDE]]></category>
		<category><![CDATA[PCB]]></category>
		<guid isPermaLink="false">https://oneearth-oneocean.com/?p=9949</guid>

					<description><![CDATA[<p>Kit Granby, Sandra Rainieri, Rie Romme Rasmussen, Michiel J.J. Kotterman, Jens Jørgen Sloth, Tommy Licht Cederberg, Alex Barranco, António Marques, Bodil Katrine Larsen, The influence of microplastics and halogenated contaminants in feed on toxicokinetics and gene expression in European seabass (Dicentrarchus labrax), Environmental Research, Volume 164, 2018, Pages 430-443, ISSN 0013-9351, Abstract: When microplastics pollute fish habitats, it may be ingested by fish, thereby contaminating fish with sorbed contaminants. The present study investigates how combinations of halogenated contaminants and microplastics associated with feed are able to alter toxicokinetics in European seabass and affect the fish. Microplastic particles (2%) were added to the feed either with sorbed contaminants or as a mixture of clean microplastics and chemical contaminants, and compared to feed containing contaminants without microplastics. For the contaminated microplastic diet, the accumulation of polychlorinated biphenyls (PCBs) and brominated flame retardants (BFRs) in fish was significantly higher, increasing up to 40 days of accumulation and then reversing to values comparable to the other diets at the end of accumulation. The significant gene expression results of liver (cyp1a, il1β, gstα) after 40 days of exposure indicate that microplastics might indeed exacerbate the toxic effects (liver metabolism, immune system, oxidative stress) of some chemical contaminants sorbed to microplastics. Seabass quickly metabolised BDE99 to BDE47 by debromination, probably mediated by deiodinase enzymes, and unlike other contaminants, this metabolism was unaffected by the presence of microplastics. For the other PCBs and BFRs, the elimination coefficients were significantly lower in fish fed the diet with contaminants sorbed to microplastic compared to the other diets. The results indicate that microplastics affects liver detoxification and lipid distribution, both of which affect the concentration of contaminants. https://drive.google.com/open?id=1c3uQVivv0FV2n_yYbEAatccNUGlVjMdo https://doi.org/10.1016/j.envres.2018.02.035.(http://www.sciencedirect.com/science/article/pii/S0013935117313610)</p>
<p>The post <a href="https://oneearth-oneocean.com/international-marine-litter-database/2021/the-influence-of-microplastics-and-halogenated-contaminants-in-feed-on-toxicokinetics-and-gene-expression-in-european-seabass-dicentrarchus-labrax/">The influence of microplastics and halogenated contaminants in feed on toxicokinetics and gene expression in European seabass (Dicentrarchus labrax)</a> appeared first on <a href="https://oneearth-oneocean.com">One Earth - One Ocean e. V.</a>.</p>
]]></description>
										<content:encoded><![CDATA[<p>Kit Granby, Sandra Rainieri, Rie Romme Rasmussen, Michiel J.J. Kotterman, Jens Jørgen Sloth,<br />
Tommy Licht Cederberg, Alex Barranco, António Marques, Bodil Katrine Larsen,</p>
<p>The influence of microplastics and halogenated contaminants in feed on toxicokinetics and gene expression in European seabass (Dicentrarchus labrax),</p>
<p>Environmental Research,<br />
Volume 164,<br />
2018,<br />
Pages 430-443,<br />
ISSN 0013-9351,</p>
<p>Abstract:</p>
<p>When microplastics pollute fish habitats, it may be ingested<br />
by fish, thereby contaminating fish with sorbed contaminants. The<br />
present study investigates how combinations of halogenated contaminants<br />
and microplastics associated with feed are able to alter toxicokinetics<br />
in European seabass and affect the fish. Microplastic particles (2%)<br />
were added to the feed either with sorbed contaminants or as a mixture<br />
of clean microplastics and chemical contaminants, and compared to feed<br />
containing contaminants without microplastics. For the contaminated<br />
microplastic diet, the accumulation of polychlorinated biphenyls (PCBs)<br />
and brominated flame retardants (BFRs) in fish was significantly higher,<br />
increasing up to 40 days of accumulation and then reversing to values<br />
comparable to the other diets at the end of accumulation. The<br />
significant gene expression results of liver (cyp1a, il1β, gstα) after<br />
40 days of exposure indicate that microplastics might indeed exacerbate<br />
the toxic effects (liver metabolism, immune system, oxidative stress) of<br />
some chemical contaminants sorbed to microplastics. Seabass quickly<br />
metabolised BDE99 to BDE47 by debromination, probably mediated by<br />
deiodinase enzymes, and unlike other contaminants, this metabolism was<br />
unaffected by the presence of microplastics. For the other PCBs and<br />
BFRs, the elimination coefficients were significantly lower in fish fed<br />
the diet with contaminants sorbed to microplastic compared to the other<br />
diets. The results indicate that microplastics affects liver<br />
detoxification and lipid distribution, both of which affect the<br />
concentration of contaminants.</p>
<p><a href="https://drive.google.com/open?id=1c3uQVivv0FV2n_yYbEAatccNUGlVjMdo">https://drive.google.com/open?id=1c3uQVivv0FV2n_yYbEAatccNUGlVjMdo</a><br />
https://doi.org/10.1016/j.envres.2018.02.035.(http://www.sciencedirect.com/science/article/pii/S0013935117313610)</p>
<p>The post <a href="https://oneearth-oneocean.com/international-marine-litter-database/2021/the-influence-of-microplastics-and-halogenated-contaminants-in-feed-on-toxicokinetics-and-gene-expression-in-european-seabass-dicentrarchus-labrax/">The influence of microplastics and halogenated contaminants in feed on toxicokinetics and gene expression in European seabass (Dicentrarchus labrax)</a> appeared first on <a href="https://oneearth-oneocean.com">One Earth - One Ocean e. V.</a>.</p>
]]></content:encoded>
					
		
		
			</item>
		<item>
		<title>Toxic Plastic Contaminates the Ocean, Beaches, and Can Poison Wildlife</title>
		<link>https://oneearth-oneocean.com/2013/2013/toxic-plastic-contaminates-the-ocean-beaches-and-can-poison-wildlife/</link>
					<comments>https://oneearth-oneocean.com/2013/2013/toxic-plastic-contaminates-the-ocean-beaches-and-can-poison-wildlife/#respond</comments>
		
		<dc:creator><![CDATA[guenther]]></dc:creator>
		<pubDate>Sun, 22 Dec 2013 18:31:26 +0000</pubDate>
				<category><![CDATA[2013]]></category>
		<category><![CDATA[fish]]></category>
		<category><![CDATA[North Pacific]]></category>
		<category><![CDATA[Reptilien / reptiles]]></category>
		<category><![CDATA[research]]></category>
		<category><![CDATA[PAH]]></category>
		<category><![CDATA[PBDE]]></category>
		<category><![CDATA[PCB]]></category>
		<category><![CDATA[Toxic Plastic]]></category>
		<guid isPermaLink="false">http://www.oneearth-oneocean.com/kb/?p=100</guid>

					<description><![CDATA[<p>http://www.seaturtles.org/article.php?id=2543 Toxic Plastic Contaminates the Ocean, Beaches, and Can Poison Wildlife Posted by Chris Pincetich, Ph.D. on November 22nd, 2013 New scientific research has confirmed fears of the global impacts of marine plastic pollution to marine life and marine ecosystems. Plastic does adsorb toxic PCBs, PBDEs and PAHs* from seawater and does transfer toxicity from adsorbed chemicals to fish that ingest them, found a new study published in Nature yesterday. Experimental fish were fed a “clean” diet, a diet with bits of virgin plastic, or a diet with bits of plastic that had adsorbed contaminants while suspended in a marine environment near San Diego, California. Toxicologists then dissected the fish and determined that there was a significant transfer of PBDEs to the fish tissue from the plastic that had adsorbed marine contaminants, and that the livers of some fish developed cellular damage. This controlled experiment confirmed the discussions I have been leading for years on the potential eco-toxic impacts of marine plastic pollution to young, endangered sea turtles. Plastic can be a vector for increased pollutant exposure to fish, and likely sea turtles and other marine wildlife, but how bad is the overall contamination of plastic in the Pacific Ocean?</p>
<p>The post <a href="https://oneearth-oneocean.com/2013/2013/toxic-plastic-contaminates-the-ocean-beaches-and-can-poison-wildlife/">Toxic Plastic Contaminates the Ocean, Beaches, and Can Poison Wildlife</a> appeared first on <a href="https://oneearth-oneocean.com">One Earth - One Ocean e. V.</a>.</p>
]]></description>
										<content:encoded><![CDATA[<pre><a href="http://www.seaturtles.org/article.php?id=2543" target="_blank" rel="noopener">http://www.seaturtles.org/article.php?id=2543</a>

Toxic Plastic Contaminates the Ocean, Beaches, and Can Poison Wildlife

Posted by Chris Pincetich, Ph.D. on November 22nd, 2013

New scientific research has confirmed fears of the global impacts of 
marine plastic pollution to marine life and marine ecosystems. Plastic 
does adsorb toxic PCBs, PBDEs and PAHs* from seawater and does transfer 
toxicity from adsorbed chemicals to fish that ingest them, found a new 
study published in Nature yesterday. Experimental fish were fed a 
“clean” diet, a diet with bits of virgin plastic, or a diet with bits of 
plastic that had adsorbed contaminants while suspended in a marine 
environment near San Diego, California. Toxicologists then dissected the 
fish and determined that there was a significant transfer of PBDEs to 
the fish tissue from the plastic that had adsorbed marine contaminants, 
and that the livers of some fish developed cellular damage. This 
controlled experiment confirmed the discussions I have been leading for 
years on the potential eco-toxic impacts of marine plastic pollution to 
young, endangered sea turtles.

Plastic can be a vector for increased pollutant exposure to fish, and 
likely sea turtles and other marine wildlife, but how bad is the overall 
contamination of plastic in the Pacific Ocean?</pre>
<p>The post <a href="https://oneearth-oneocean.com/2013/2013/toxic-plastic-contaminates-the-ocean-beaches-and-can-poison-wildlife/">Toxic Plastic Contaminates the Ocean, Beaches, and Can Poison Wildlife</a> appeared first on <a href="https://oneearth-oneocean.com">One Earth - One Ocean e. V.</a>.</p>
]]></content:encoded>
					
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