Carlo Giacomo Avio, Stefania Gorbi, Massimo Milan, Maura Benedetti,
\nDaniele Fattorini, Giuseppe d’Errico, Marianna Pauletto, Luca
\nBargelloni, Francesco Regoli, Pollutants bioavailability and
\ntoxicological risk from microplastics to marine mussels, Environmental
\nPollution, Volume 198, March 2015, Pages 211-222, ISSN 0269-7491,
\nhttp:\/\/dx.doi.org\/10.1016\/j.envpol.2014.12.021.
\n(http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0269749114005211)
\nAbstract: Microplastics represent a growing environmental concern for
\nthe oceans due to their potential of adsorbing chemical pollutants, thus
\nrepresenting a still unexplored source of exposure for aquatic
\norganisms. In this study polyethylene (PE) and polystyrene (PS)
\nmicroplastics were shown to adsorb pyrene with a time and dose-dependent
\nrelationship. Results also indicated a marked capability of contaminated
\nmicroplastics to transfer this model PAH to exposed mussels Mytilus
\ngalloprovincialis; tissue localization of microplastics occurred in
\nhaemolymph, gills and especially digestive tissues where a marked
\naccumulation of pyrene was also observed. Cellular effects included
\nalterations of immunological responses, lysosomal compartment,
\nperoxisomal proliferation, antioxidant system, neurotoxic effects, onset
\nof genotoxicity; changes in gene expression profile was also
\ndemonstrated through a new DNA microarray platform. The study provided
\nthe evidence that microplastics adsorb PAHs, emphasizing an elevated
\nbioavailability of these chemicals after the ingestion, and the
\ntoxicological implications due to responsiveness of several molecular
\nand cellular pathways to microplastics.
\nKeywords: Microplastic; PAHs; Bioavailability; Biomarkers; Mussels;
\nTranscriptomics<\/p>\n","protected":false},"excerpt":{"rendered":"
Carlo Giacomo Avio, Stefania Gorbi, Massimo Milan, Maura Benedetti, Daniele Fattorini, Giuseppe d’Errico, Marianna Pauletto, Luca Bargelloni, Francesco Regoli, Pollutants bioavailability and toxicological risk from microplastics to marine mussels, Environmental Pollution, Volume 198, March 2015, Pages 211-222, ISSN 0269-7491, http:\/\/dx.doi.org\/10.1016\/j.envpol.2014.12.021. (http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0269749114005211) Abstract: Microplastics represent a growing environmental concern for the oceans due to their potential of adsorbing chemical pollutants, thus representing a still unexplored source of exposure for aquatic organisms. In this study polyethylene (PE) and polystyrene (PS) microplastics were shown to adsorb pyrene with a time and dose-dependent relationship. Results also indicated a marked capability of contaminated microplastics to transfer this model PAH to exposed mussels Mytilus galloprovincialis; tissue localization of microplastics occurred in haemolymph, gills and especially digestive tissues where a marked accumulation of pyrene was also observed. Cellular effects included alterations of immunological responses, lysosomal compartment, peroxisomal proliferation, antioxidant system, neurotoxic effects, onset of genotoxicity; changes in gene expression profile was also demonstrated through a new DNA microarray platform. The study provided the evidence that microplastics adsorb PAHs, emphasizing an elevated bioavailability of these chemicals after the ingestion, and the toxicological implications due to responsiveness of several molecular and cellular pathways to microplastics. Keywords: Microplastic; PAHs; Bioavailability; Biomarkers; Mussels; Transcriptomics<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3476,3533,3423],"tags":[1445,3534,2290,3535],"yoast_head":"\n