Influence of microplastics on the accumulation and chronic toxic effects of cadmium in zebrafish (Danio rerio),

Chemosphere,
2018,
ISSN 0045-6535,

Abstract:

As the accumulation of microplastics (MPs) in the environment
continues to rise, more concerns focus on the health risk of combined
exposure to MPs and other contaminants. The aim of this study is to
investigate the influences of MPs on the tissue-accumulation of cadmium
(Cd) in zebrafish and explore the related chronic toxic effects induced
by combined exposure of Cd and MPs. After co-exposure to MPs and Cd for
3 weeks, 20 and 200 μg/L MPs increased the accumulation of Cd in
zebrafish livers (46% and 184%), guts (10% and 25%) and gills (9% and
46%). The Cd accumulation was gill > gut > liver. Comprehensive analyzes
of biochemical biomarkers, histopathological observation and functional
gene expression firstly demonstrated that the presence of MPs enhanced
the toxicity of Cd on zebrafish and the combined exposure caused
oxidative damage and inflammation in zebrafish tissues. Collectively,
our results highlight the chronic effects of combined exposure to MPs
and heavy metals.

https://drive.google.com/open?id=19QNBzSwS5Fa24OhiUuVA6i0mES68Q5vh
https://doi.org/10.1016/j.chemosphere.2018.03.145.(http://www.sciencedirect.com/science/article/pii/S0045653518305629)

The post Influence of microplastics on the accumulation and chronic toxic effects of cadmium in zebrafish (Danio rerio) appeared first on One Earth - One Ocean e. V..

Abstract:

As the accumulation of microplastics (MPs) in the environment
continues to rise, more concerns focus on the health risk of combined
exposure to MPs and other contaminants. The aim of this study is to
investigate the influences of MPs on the tissue-accumulation of cadmium
(Cd) in zebrafish and explore the related chronic toxic effects induced
by combined exposure of Cd and MPs. After co-exposure to MPs and Cd for
3 weeks, 20 and 200 μg/L MPs increased the accumulation of Cd in
zebrafish livers (46% and 184%), guts (10% and 25%) and gills (9% and
46%). The Cd accumulation was gill > gut > liver. Comprehensive analyzes
of biochemical biomarkers, histopathological observation and functional
gene expression firstly demonstrated that the presence of MPs enhanced
the toxicity of Cd on zebrafish and the combined exposure caused
oxidative damage and inflammation in zebrafish tissues. Collectively,
our results highlight the chronic effects of combined exposure to MPs
and heavy metals.
Keywords: Microplastics; Heavy metal; Combined exposure; Chronic
toxicity; Zebrafish

https://drive.google.com/open?id=19QNBzSwS5Fa24OhiUuVA6i0mES68Q5vh
https://doi.org/10.1016/j.chemosphere.2018.03.145.(http://www.sciencedirect.com/science/article/pii/S0045653518305629)

The post Influence of microplastics on the accumulation and chronic toxic effects of cadmium in zebrafish (Danio rerio) appeared first on One Earth - One Ocean e. V..

Influence of microplastics on the accumulation and chronic toxic effects of cadmium in zebrafish (Danio rerio),
Chemosphere,

Volume 202,
2018,
Pages 514-520,
ISSN 0045-6535,

Abstract:

As the accumulation of microplastics (MPs) in the environment continues to rise, more concerns focus on the health risk of combinedexposure to MPs and other contaminants.
The aim of this study is to investigate the influences of MPs on the tissue-accumulation of cadmium
(Cd) in zebrafish and explore the related chronic toxic effects induced by combined exposure of Cd and MPs.
After co-exposure to MPs and Cd for 3 weeks, 20 and 200 μg/L MPs increased the accumulation of Cd in
zebrafish livers (46% and 184%), guts (10% and 25%) and gills (9% and 46%).
The Cd accumulation was gill > gut > liver. Comprehensive analyzesof biochemical biomarkers, histopathological observation and functionalgene expression firstly demonstrated that the presence of MPs enhanced
the toxicity of Cd on zebrafish and the combined exposure caused oxidative damage and inflammation in zebrafish tissues.
Collectively, our results highlight the chronic effects of combined exposure to MPs and heavy metals.

https://drive.google.com/open?id=19QNBzSwS5Fa24OhiUuVA6i0mES68Q5vh
https://doi.org/10.1016/j.chemosphere.2018.03.145.(http://www.sciencedirect.com/science/article/pii/S0045653518305629)

The post Influence of microplastics on the accumulation and chronic toxic effects of cadmium in zebrafish (Danio rerio), Chemosphere, appeared first on One Earth - One Ocean e. V..

Evaluation of uptake and chronic toxicity of virgin polystyrene microbeads in freshwater zebra mussel Dreissena polymorpha (Mollusca: Bivalvia),

Science of The Total Environment, Volumes 631–632, 1 August 2018, Pages 778-788, ISSN 0048-9697,

Abstract:

Microplastics (MPs), plastic debris smaller than 5 mm, are widely found in both marine and freshwater ecosystems. However, few studies regarding their hazardous effects on inland water organisms, have been conducted.
For this reason, the aim of our research was the evaluation of uptake and chronic toxicity of two mixtures (MIXs) of virgin polystyrene microbeads (PMs) of 10 μm and 1 μm in size (MIX 1, with 5 × 105 of 1 μm size
PMs/L and 5 × 105 of 10 μm size PMs/L, and MIX 2 with 2 × 106 of 1 μm size PMs/L and 2 × 106 of 10 μm size PMs/L) on freshwater zebra mussel Dreissena polymorpha (Mollusca: Bivalvia) during 6 exposure days.

The PM uptake in the mussel body and hemolymph was assessed using confocal microscopy, while the chronic toxicity of PMs was evaluated on exposed mussels using a comprehensive battery of biomarkers of cellular
stress, oxidative damage and neuro- genotoxicity. Confocal microscopy analyses showed that MPs concentrated in the gut lumen of exposed mussels, absorbed and transferred firstly in the tissues and then in the hemolymph. The results revealed that PMs do not produce oxidative stress and genetic damage, with the exception of a significant modulation of catalase and glutathione peroxidase activities in mussels exposed to MIX 1. Regarding neurotoxicity, we observed only a significant increase of dopamine concentration in mussels exposed to both MIXs, suggesting a
possible implication of this neurotransmitter in an elimination process of accumulated PMs. This research represents a first study about the evaluation of virgin MP toxicity in zebra mussel and more research is warranted concerning the long term neurological effects of virgin MPs.

https://drive.google.com/open?id=1AndOjzImdaKg_VAnnO05yjGKuUUDKL3V

https://doi.org/10.1016/j.scitotenv.2018.03.075.(https://www.sciencedirect.com/science/article/pii/S0048969718308295)

The post Evaluation of uptake and chronic toxicity of virgin polystyrene microbeads in freshwater zebra mussel Dreissena polymorpha (Mollusca: Bivalvia appeared first on One Earth - One Ocean e. V..